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Structure of 1416784-71-8
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This 4-(3-hydroxyazetidin-1-yl)benzoic acid integrates a polar, bench-stable azetidine ring with a carboxylic acid handle, enabling efficient conjugation in medicinal chemistry. The hydroxyl-bearing heterocycle enhances solubility and metabolic stability, while the para-substituted aromatic scaffold supports modular derivatization for target-directed probe development.
4-(3-Hydroxyazetidin-1-yl)benzoic acid serves as a versatile building block for medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization protocols. The azetidine ring imparts metabolic stability and enhanced solubility, while the carboxylic acid facilitates conjugation in peptide and macrocyclic scaffolds. Bench-stable and amenable to purification via recrystallization or chromatography, it functions effectively in both solution-phase synthesis and solid-phase workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: