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Structure of 36070-80-1
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5-Chloro-2-pyrazinecarboxylic acid features a chlorinated pyrazine core with a carboxylic acid group at the 2-position, enabling direct conjugation in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity under standard conditions.
5-Chloro-2-pyrazinecarboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the pyrazine core. Its carboxylic acid group facilitates amide formation, esterification, and coupling reactions under standard conditions, while the chloro substituent supports nucleophilic aromatic substitution and transition-metal-catalyzed cross-couplings. The molecule exhibits good bench stability and is readily purified by recrystallization, making it suitable for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: