Desamino lenalidomide-6-OH

Name: Desamino lenalidomide-6-OH
Brand: ChemScene
Availability: InStock
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CAS No. 1416990-09-4
Cat. No. CS-0436509
Purity≥98%
MDL No.MFCD34407392

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1416990-09-4

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Description

This piperidine-2,6-dione derivative features a hydroxyisoindolinone moiety that enhances solubility and enables hydrogen bonding in synthetic intermediates. The scaffold integrates robust stability with functional versatility for medicinal chemistry applications, particularly in kinase inhibitor design and peptide mimetics.

Application

3-(6-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione serves as a versatile scaffold for constructing bioactive heterocycles, leveraging its dual functionality for orthogonal derivatization. The isoindolinone core enables facile functional group interconversions, while the piperidinedione moiety provides structural rigidity and hydrogen-bonding capacity. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of complex molecular architectures in medicinal chemistry workflows.

General Information

CAS No. 1416990-09-4
Cat. No. CS-0436509
Purity ≥98%
MDL No. MFCD34407392
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₂N₂O₄
Molecular Weight 260.25
Synonym(s) None
SMILES O=C1NC(=O)C(N2C(=O)C3=CC(O)=CC=C3C2)CC1

Computational Chemistry Data

TPSA 86.71
LogP -0.4067
H_Acceptors 6
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indolin compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Life Science PROTAC Ligands for E3 Ligase

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Desamino lenalidomide-6-OH

CAS No. 1416990-09-4

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