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Structure of 14172-55-5
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1-(Phenylsulphonyl)piperazine features a rigid, electron-deficient phenylsulphonyl group linked to a versatile piperazine scaffold. This combination imparts enhanced solubility and metabolic stability, enabling efficient integration into bioactive molecules. The moiety serves as a key pharmacophore in medicinal chemistry, particularly for modulating target affinity and improving pharmacokinetic profiles in drug discovery campaigns.
1-(Phenylsulphonyl)piperazine serves as a versatile building block in medicinal chemistry, enabling the construction of sulfonamide-containing heterocycles through standard functional group manipulations. Its phenylsulphonyl moiety imparts good bench stability and facilitates downstream transformations such as nucleophilic substitution or cross-coupling reactions. The piperazine scaffold provides multiple points for derivatization, supporting diverse molecular architectures in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: