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CS-W001157 4
Total: USD 88.00

6-Bromo-2-fluoro-3-nitropyridine

  • CAS No. 1417333-87-9

  • Cat. No. CS-0376054
  • Purity≥96%
  • MDL No.MFCD28669853

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-fluoro-3-nitropyridine|CS-0376054

Structure of 1417333-87-9

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General Information

  • CAS No. 1417333-87-9
  • Cat. No. CS-0376054
  • Purity ≥96%
  • MDL No. MFCD28669853
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂BrFN₂O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=[N+](C1=CC=C(Br)N=C1F)[O-]

Description

6-Bromo-2-fluoro-3-nitropyridine features a trifunctional pyridine core with bromo, fluoro, and nitro groups positioned for orthogonal reactivity. This electron-deficient heterocycle enables direct coupling in cross-coupling protocols and serves as a key intermediate in medicinal chemistry. The molecule exhibits bench-stable handling under standard conditions.

Application

6-Bromo-2-fluoro-3-nitropyridine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. Its orthogonal halogen (Br, F) and nitro groups enable sequential cross-coupling reactions, palladium-catalyzed transformations, and selective reductions. The molecule exhibits good bench stability and facilitates efficient functionalization in late-stage diversification efforts within medicinal chemistry and agrochemical research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   56.03
  • LogP   1.8914
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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