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Structure of 58602-02-1
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2,6-Difluoro-3-nitropyridine features a trifunctional pyridine core with electron-withdrawing fluorine and nitro groups positioned for orthogonal reactivity. This bench-stable scaffold enables direct coupling in late-stage functionalization, offering high regioselectivity in cross-coupling and nucleophilic substitution workflows.
2,6-Difluoro-3-nitropyridine serves as a versatile building block in medicinal chemistry, enabling regioselective functionalization at the C5 position via nucleophilic substitution. Its electron-deficient pyridine core enhances reactivity toward amines and thiols, facilitating the construction of key heterocyclic scaffolds. Bench-stable and readily purified by column chromatography, it supports scalable synthesis of API intermediates and advanced intermediates in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: