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Structure of 1422449-68-0
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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1,8-naphthyridin-2(1H)-one features a boronate ester handle appended to a dihydro-1,8-naphthyridinone core, enabling efficient Suzuki-Miyaura coupling. This bench-stable, moisture-tolerant scaffold integrates readily into complex molecular architectures, delivering structural diversity in medicinal chemistry and materials synthesis.
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1,8-naphthyridin-2(1H)-one serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and compatibility with diverse functional groups enable efficient construction of biaryl architectures. The 3,4-dihydro-1,8-naphthyridin-2-one core provides a privileged scaffold in medicinal chemistry, while the diborane moiety facilitates reliable coupling with aryl and heteroaryl halides. This compound functions as a key intermediate in the synthesis of targeted small molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: