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Structure of 1427397-15-6
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Methyl 2-(2-bromo-6-fluorophenyl)acetate features a bromo- and fluoro-substituted phenyl ring that imparts enhanced electron-withdrawing character, enabling efficient coupling in cross-coupling reactions. The ester functionality provides synthetic versatility for downstream transformations. This bench-stable reagent facilitates the construction of complex arylated scaffolds under standard conditions.
Methyl 2-(2-bromo-6-fluorophenyl)acetate serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its ortho-halogenated aryl moiety. The ester group provides a handle for further functionalization, while the fluorine substituent enhances metabolic stability and modulates electronic properties. This compound exhibits good bench stability and facilitates efficient synthesis of complex heterocyclic scaffolds and bioactive molecules through standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: