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Structure of 14282-78-1
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4-Methylthiophene-2-carboxylic acid features a thiophene ring bearing a methylthio group at the 4-position and a carboxylic acid at the 2-position, offering a distinct combination of electron-rich heterocyclic character and polar functionality. This structure enables direct incorporation into bioactive scaffolds and conjugated materials, particularly where enhanced solubility and stability are required under standard bench conditions.
4-Methylthiophene-2-carboxylic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its thiophene core provides enhanced metabolic stability and π-stacking capability, while the carboxylic acid functionality enables direct coupling reactions or derivatization via standard amide, ester, or acyl chloride transformations. The methyl group at the 4-position offers a handle for selective functionalization and contributes to favorable solubility and crystallinity during purification. This compound exhibits good bench stability and compatibility with common reaction conditions in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H319
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Precautionary Statements : P261-P264-P272-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: