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Structure of 936917-36-1
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Iodo-PEG3-N3 is a trifunctional linker featuring a reactive iodide handle, a three-ethylene glycol spacer, and a terminal azide group. This combination enables efficient conjugation in bioorthogonal reactions, with the PEG3 segment enhancing solubility and reducing non-specific binding. Ideal for site-specific labeling in protein and biomolecule engineering workflows under standard conditions.
Iodo-PEG3-N₃ serves as a versatile bifunctional linker for bioconjugation and click chemistry applications. The iodide group enables site-specific alkylation of nucleophilic residues (e.g., cysteine) in proteins or peptides, while the terminal azide facilitates highly selective copper-catalyzed or strain-promoted cycloadditions. Its PEG3 spacer provides solubility and reduced aggregation, enhancing performance in aqueous environments. This reagent is bench-stable, easily purified by chromatography, and widely used in the construction of antibody-drug conjugates, peptide-protein hybrids, and functionalized surfaces.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: