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CS-W001157 4
Total: USD 88.00

Iodo-PEG3-N3

  • CAS No. 936917-36-1

  • Cat. No. CS-0108847
  • Purity≥97%
  • MDL No.MFCD25969270
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Iodo-PEG3-N3|CS-0108847

Structure of 936917-36-1

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Description

Iodo-PEG3-N3 is a trifunctional linker featuring a reactive iodide handle, a three-ethylene glycol spacer, and a terminal azide group. This combination enables efficient conjugation in bioorthogonal reactions, with the PEG3 segment enhancing solubility and reducing non-specific binding. Ideal for site-specific labeling in protein and biomolecule engineering workflows under standard conditions.

Application

Iodo-PEG3-N₃ serves as a versatile bifunctional linker for bioconjugation and click chemistry applications. The iodide group enables site-specific alkylation of nucleophilic residues (e.g., cysteine) in proteins or peptides, while the terminal azide facilitates highly selective copper-catalyzed or strain-promoted cycloadditions. Its PEG3 spacer provides solubility and reduced aggregation, enhancing performance in aqueous environments. This reagent is bench-stable, easily purified by chromatography, and widely used in the construction of antibody-drug conjugates, peptide-protein hybrids, and functionalized surfaces.

General Information

  • CAS No. 936917-36-1
  • Cat. No. CS-0108847
  • Purity ≥97%
  • MDL No. MFCD25969270
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆IN₃O₃
  • Molecular Weight 329.14
  • Synonym(s) None
  • SMILES ICCOCCOCCOCCN=[N+]=[N-]

Computational Chemistry Data

  • TPSA   76.45
  • LogP   1.7815
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   11

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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