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Structure of 1428776-57-1
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Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate is a chiral pyrrolidine derivative featuring a bench-stable tert-butyl carbamate protecting group and a sterically hindered trifluoromethyl substituent. This configuration enables efficient incorporation into peptidomimetic scaffolds and bioactive molecules, where the amino functionality facilitates downstream derivatization under standard conditions.
Tert-butyl (3S,4R)-3-amino-4-(trifluoromethyl)pyrrolidine-1-carboxylate serves as a stereochemically defined building block for the synthesis of bioactive heterocycles. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the protected amine enables sequential functionalization. The compound exhibits excellent bench stability and facilitates efficient coupling reactions, making it a practical choice for medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: