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N-Boc-Iminodipropionic acid

  • CAS No. 143766-89-6

  • Cat. No. CS-0154813
  • Purity≥97%
  • MDL No.MFCD11226793

*For research and further manufacturing use only, not for direct human use.

N-Boc-Iminodipropionic acid|CS-0154813

Structure of 143766-89-6

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General Information

  • CAS No. 143766-89-6
  • Cat. No. CS-0154813
  • Purity ≥97%
  • MDL No. MFCD11226793
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₆
  • Molecular Weight 261.27
  • Synonym(s) N-Boc-3,3'-azanediyldipropionic acid
  • SMILES CC(C)(C)OC(=O)N(CCC(=O)O)CCC(=O)O

Description

N-Boc-Iminodipropionic acid features a protected imino group flanked by two propionic acid chains, offering a stable, moisture-tolerant scaffold for peptide synthesis. This bifunctional building block integrates readily into peptidomimetic architectures and facilitates efficient coupling under standard conditions.

Application

N-Boc-Iminodipropionic acid serves as a versatile building block for the synthesis of peptide-like scaffolds and heterocyclic systems. Its well-defined imino functionality enables efficient coupling reactions, while the Boc group provides reliable protection under standard conditions. The molecule exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in multistep syntheses involving amide bond formation and ring closure processes.

Synthesis

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      N-Boc-Iminodipropionic acid|CS-0154813
      143766-89-6

    References

    • Nakatani; Sando; Kumasawa; Kikuchi; Saito Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12650 - 12657
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    • In-stock
      N-Boc-Iminodipropionic acid|CS-0154813
      143766-89-6

    References

    • Uhrich, Kathryn E.; Frechet, Jean M. J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1623 - 1630
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    References

    • Uhrich, Kathryn E.; Frechet, Jean M. J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1623 - 1630

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   104.14
  • LogP   1.1729
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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