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CS-W001157 4
Total: USD 88.00

(E)-3-(2-Thiazolyl)acrylic Acid

  • CAS No. 144163-52-0

  • Cat. No. CS-0784772
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-3-(2-Thiazolyl)acrylic Acid|CS-0784772

Structure of 144163-52-0

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General Information

  • CAS No. 144163-52-0
  • Cat. No. CS-0784772
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NO₂S
  • Molecular Weight 155.17
  • Synonym(s) None
  • SMILES OC(=O)\C=C\C1=NC=CS1

Description

(E)-3-(2-Thiazolyl)acrylic acid features a conjugated enoic acid system linked to a heterocyclic thiazole ring, enabling robust participation in Michael additions and Diels-Alder cycloadditions. This configuration imparts enhanced stability and facilitates integration into bioactive scaffolds requiring planar, electron-deficient π-systems.

Application

(E)-3-(2-Thiazolyl)acrylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to thiazole-containing scaffolds via standard Michael additions and cycloaddition reactions. Its conjugated enoic acid functionality exhibits robust bench stability and facilitates straightforward purification, while the thiazole moiety provides excellent functional group tolerance in coupling and derivatization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.2409
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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