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Structure of 1445-56-3
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3-Chloropyridazine-4-carbonitrile features a dual functional group architecture with a chlorine atom at the 3-position and a nitrile group at the 4-position, enabling selective coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and agrochemical scaffolds under standard conditions.
3-Chloropyridazine-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via nucleophilic substitution. Its dual electron-withdrawing groups—chlorine and nitrile—enhance reactivity in cross-coupling and amination reactions, facilitating access to substituted pyridazinones and heterocyclic scaffolds common in agrochemicals and pharmaceuticals. The compound exhibits good bench stability and is amenable to purification by recrystallization or flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: