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Structure of 1446486-10-7
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This boronate moiety features a trifluoromethyl group that enhances electron-withdrawing character and stability, while the chlorine substituent enables selective cross-coupling. Designed for efficient Suzuki-Miyaura reactions under standard conditions, it delivers robust performance in constructing complex aryl scaffolds with high functional group tolerance.
(2-Chloro-6-(trifluoromethyl)pyridin-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the boronic acid functionality offers reliable reactivity with aryl halides under mild conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: