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Structure of 66016-28-2
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3-Phenylcyclobutanecarboxylic acid features a rigid cyclobutane core fused to a phenyl ring, delivering enhanced structural stability and defined spatial orientation. This configuration supports precise molecular recognition in synthetic applications. The carboxylic acid group enables direct derivatization or salt formation for improved solubility and handling. Its bench-stable nature facilitates use in multi-step synthesis without degradation.
3-Phenylcyclobutanecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds through standard functional group transformations. Its rigid cyclobutane core imparts conformational constraint, enhancing target binding affinity in drug discovery. The carboxylic acid functionality facilitates direct coupling reactions and derivatization, while the phenyl substituent offers π-stacking potential and synthetic handle for further modification. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P501
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Lot numbers can be found on the outside label of a product: