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CS-W001157 4
Total: USD 88.00

2-Amino-4-methoxybenzenethiol

  • CAS No. 14482-32-7

  • Cat. No. CS-0463807
  • Purity≥98%
  • MDL No.MFCD17014600

*For research and further manufacturing use only, not for direct human use.

2-Amino-4-methoxybenzenethiol|CS-0463807

Structure of 14482-32-7

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General Information

  • CAS No. 14482-32-7
  • Cat. No. CS-0463807
  • Purity ≥98%
  • MDL No. MFCD17014600
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NOS
  • Molecular Weight 155.22
  • Synonym(s) Benzenethiol,2-amino-4-methoxy
  • SMILES COC1=CC(=C(C=C1)S)N

Synthesis

  • Route1
    • 1-Chloro-4-methoxy-2-nitrobenzene Iguratimod Impurity|CS-0514516
      10298-80-3
    • ~99%
    • 2-Amino-4-methoxybenzenethiol|CS-0463807
      14482-32-7

    References

    • UNIVERSITY OF PITTSBURGH Patent: WO2007/64773 A2, 2007 ; Location in patent: Page/Page column 52-53 ;
  • Route2
    • 5-Methoxy-2-methylbenzo[d]thiazole|CS-W017258
      2941-69-7
    • ~83%
    • 2-Amino-4-methoxybenzenethiol|CS-0463807
      14482-32-7

    References

    • Hodson, Stephen J.; Bishop, Michael J.; Speake, Jason D.; Navas III, Frank; Garrison, Deanna T.; Bigham, Eric C.; Saussy Jr., David L.; Liacos, James A.; Irving, Paul E.; Jeffrey Gobel; Sherman, Bryan W. Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2229 - 2239
  • Route3

    References

    • Inoue, Hirozumi; Konda, Mikihiko; Hashiyama, Tomiki; Otsuka, Hisao; Watanabe, Akishige; Gaino, Mitsunori; Takahashi, Kaoru; Date, Tadamasa; Okamura, Kimio; Takeda, Mikio; Narita, Hiroshi; Murata, Sakae; Odawara, Akio; Sasaki, Haruhiko; Nagao, Taku Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 6 p. 1008 - 1026

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.5661
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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