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Structure of 144822-82-2
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2,3-Dihydro-4-benzofuranol features a fused bicyclic structure with a hydroxyl group at the 4-position, offering enhanced solubility and stability compared to its aromatic counterparts. This bench-stable scaffold integrates readily into synthetic sequences requiring oxygenated heterocyclic motifs.
2,3-Dihydro-4-benzofuranol serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its phenolic hydroxyl group facilitates direct derivatization and orthogonal functionalization, while the saturated furan ring enhances metabolic stability and solubility. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it a practical building block for lead optimization and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: