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Structure of 144825-18-3
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2-[4-(Hydroxymethyl)phenyl]acetonitrile features a para-hydroxymethyl-substituted phenyl ring linked to a nitrile-bearing acetonide chain, enabling integration into functionalized aromatic scaffolds. The hydroxymethyl group offers a handle for derivatization, while the nitrile moiety provides synthetic versatility in cross-coupling and reduction reactions. This compound exhibits bench-stable handling characteristics and compatibility with standard organic synthesis protocols.
2-[4-(Hydroxymethyl)phenyl]acetonitrile serves as a versatile building block for medicinal chemistry and materials synthesis, enabling efficient access to biaryl scaffolds via palladium-catalyzed coupling reactions. The nitrile group facilitates downstream functionalization through hydrolysis or reduction, while the pendant hydroxymethyl moiety supports derivatization via oxidation or protection. Its bench-stable nature and compatibility with standard reaction conditions make it suitable for scalable synthesis and parallel library construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: