(S,R,S)-AHPC

Name: (S,R,S)-AHPC
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1448297-52-6
Cat. No. CS-0101174
Purity≥97%
MDL No.MFCD29049827

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

(S,R,S)-AHPC is a chiral auxiliary featuring three stereocenters that enables asymmetric synthesis through predictable stereocontrol. This configuration facilitates high diastereoselective transformations, particularly in enantioselective alkylation and conjugate addition reactions. The scaffold integrates seamlessly into complex molecule assembly workflows under standard bench conditions.

Application

(S,R,S)-AHPC serves as a well-defined chiral building block for the synthesis of bioactive heterocycles and peptidomimetics. Its three stereocenters enable precise stereocontrol in macrocyclization and coupling reactions, while its amine and carboxylic acid functionalities offer direct handles for conjugation. The compound exhibits excellent bench stability and compatibility with standard peptide coupling protocols, facilitating efficient access to complex scaffolds in medicinal chemistry campaigns.

General Information

CAS No. 1448297-52-6
Cat. No. CS-0101174
Purity ≥97%
MDL No. MFCD29049827
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₃₀N₄O₃S
Molecular Weight 430.56
Synonym(s) VH032-NH2; VHL ligand 1
SMILES O=C([C@H](C[C@@H](O)C1)N1C([C@@H](N)C(C)(C)C)=O)NCC2=CC=C(C(SC=N3)=C3C)C=C2

Computational Chemistry Data

TPSA 108.55
LogP 2.06992
H_Acceptors 6
H_Donors 3
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science PROTAC Ligands for E3 Ligase

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

Key Words

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(S,R,S)-AHPC

CAS No. 1448297-52-6

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