Fmoc-Asp-OMe

Name: Fmoc-Asp-OMe
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 145038-52-4
Cat. No. CS-W022722
Purity≥97%
MDL No.MFCD03701473

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 145038-52-4

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Description

Fmoc-Asp-OMe features a protected aspartic acid residue with orthogonal functionality for peptide synthesis. The Fmoc group enables base-labile N-terminal deprotection, while the methyl ester stabilizes the C-terminal carboxylate. This combination facilitates efficient coupling and selective modification in solid-phase workflows, offering reliable handling and compatibility with standard protocols.

Application

Fmoc-Asp-OMe serves as a key building block in solid-phase peptide synthesis, offering orthogonal protection for both the α-amino and side-chain carboxyl groups. The Fmoc group enables efficient base-labile deprotection, while the methyl ester prevents unwanted side reactions during coupling. Its bench-stable nature and compatibility with standard coupling reagents facilitate reliable incorporation into peptide sequences, particularly in the synthesis of acidic or complex peptide scaffolds.

General Information

CAS No. 145038-52-4
Cat. No. CS-W022722
Purity ≥97%
MDL No. MFCD03701473
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₁₉NO₆
Molecular Weight 369.37
Synonym(s) None
SMILES O=C(O)C[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(OC)=O

Computational Chemistry Data

TPSA 101.93
LogP 2.5414
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Aspartic acid and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Asp-OMe

CAS No. 145038-52-4

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