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Structure of 70593-57-6
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4,6-Dichloronicotinamide delivers a highly electron-deficient pyridine scaffold ideal for coupling reactions in agrochemical and pharmaceutical synthesis. The dual chlorine substituents enhance reactivity at the amide nitrogen and provide strategic handles for further functionalization under mild conditions. This bench-stable compound integrates efficiently into complex molecular architectures with predictable regiochemistry.
4,6-Dichloronicotinamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution and coupling reactions. Its dual chloro substituents at the 4- and 6-positions provide orthogonal reactivity for sequential functionalization, while the amide group offers stability and compatibility with diverse reaction conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: