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Structure of 1452-16-0
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2-Cyanothiazole serves as a pivotal heterocyclic scaffold in medicinal chemistry, integrating a nitrile group directly adjacent to a thiazole ring. This arrangement imparts enhanced polarity and metabolic stability, enabling efficient incorporation into bioactive molecules. The electron-deficient nature of the ring facilitates targeted covalent interactions, while the bench-stable structure supports straightforward handling in synthetic workflows.
2-Cyanothiazole serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling efficient access to thiazole-based scaffolds through electrophilic substitution and transition-metal-catalyzed coupling reactions. Its nitrile group enhances functional group tolerance and provides a handle for downstream derivatization, while the ring exhibits robust bench stability and compatibility with standard purification methods. This compound functions effectively in the construction of medicinally relevant heterocycles and advanced intermediates for pharmaceutical development.
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H332-H311-H315-H319-H335-H373
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: