Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 145934-81-2
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
5-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine is a heterocyclic scaffold featuring a chlorine substituent at the 5-position and a methyl group at the 2-position, enhancing electronic modulation and steric profile. This electron-deficient core integrates readily into medicinal chemistry campaigns, serving as a key building block for kinase inhibitors and bioactive small molecules. The fused pyrrole-pyridine system confers metabolic stability and favorable solubility under standard conditions.
5-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to complex scaffolds via palladium-catalyzed cross-coupling reactions. Its chloro group facilitates C–C bond formation under standard Suzuki and Negishi conditions, while the methyl substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability, simplifies purification, and demonstrates broad functional group tolerance, making it well-suited for iterative synthesis of kinase inhibitors and other bioactive molecules.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: