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Structure of 866546-07-8
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5-Chloro-7-azaindole is a heterocyclic building block featuring a chlorine substituent at the 5-position and a nitrogen atom at the 7-position of the indole scaffold. This electron-deficient core enhances reactivity in cross-coupling processes and serves as a key scaffold for medicinal chemistry, particularly in kinase inhibitor development and bioactive molecule design.
5-Chloro-7-azaindole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its electron-deficient pyridine-like core facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions. The chlorine substituent provides a handle for palladium-mediated functionalization, while the nitrogen-rich framework enhances solubility and hydrogen-bonding capacity. Bench-stable and compatible with diverse reaction conditions, it functions effectively in parallel synthesis campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: