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5-Chloro-7-azaindole

  • CAS No. 866546-07-8

  • Cat. No. CS-B0095
  • Purity≥98%
  • MDL No.MFCD06659676
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-7-azaindole|CS-B0095

Structure of 866546-07-8

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Description

5-Chloro-7-azaindole is a heterocyclic building block featuring a chlorine substituent at the 5-position and a nitrogen atom at the 7-position of the indole scaffold. This electron-deficient core enhances reactivity in cross-coupling processes and serves as a key scaffold for medicinal chemistry, particularly in kinase inhibitor development and bioactive molecule design.

Application

5-Chloro-7-azaindole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its electron-deficient pyridine-like core facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions. The chlorine substituent provides a handle for palladium-mediated functionalization, while the nitrogen-rich framework enhances solubility and hydrogen-bonding capacity. Bench-stable and compatible with diverse reaction conditions, it functions effectively in parallel synthesis campaigns and API development workflows.

General Information

  • CAS No. 866546-07-8
  • Cat. No. CS-B0095
  • Purity ≥98%
  • MDL No. MFCD06659676
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClN₂
  • Molecular Weight 152.58
  • Synonym(s) 5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine
  • SMILES ClC1=CC2=C(NC=C2)N=C1

Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.2163
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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