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Structure of 1459778-94-9
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3,5-Difluoro-4-(trifluoromethyl)phenyl boronic acid features a trifluoromethyl group flanked by two fluorine substituents, delivering enhanced electron-withdrawing character and improved stability. This combination enables efficient Suzuki-Miyaura coupling under standard conditions, with robust performance in late-stage functionalization of heterocyclic scaffolds.
3,5-Difluoro-4-(trifluoromethyl)phenyl boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its trifluoromethyl and difluoro substituents enhance metabolic stability and modulate electronic properties, making it valuable for constructing fluorinated aromatic scaffolds in pharmaceutical and agrochemical research. The boronic acid functionality offers excellent bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: