N-Benzoyl-L-leucine

Name: N-Benzoyl-L-leucine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1466-83-7
Cat. No. CS-0201820
Purity≥98%
MDL No.MFCD00190766

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1466-83-7

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Description

N-Benzoyl-L-leucine integrates a benzoyl group at the nitrogen terminus of L-leucine, delivering a sterically hindered, electron-rich scaffold ideal for peptide coupling and bioconjugation. This bench-stable derivative enhances solubility in organic media while maintaining compatibility with standard amide bond formation protocols.

Application

N-Benzoyl-L-leucine serves as a stable, bench-ready chiral building block for peptide synthesis and medicinal chemistry. Its aromatic acyl group enhances solubility and provides orthogonal protection for the amine, enabling selective deprotection in complex sequences. The leucine side chain offers hydrophobic character useful in bioactive molecule design, while the N-benzoyl moiety facilitates purification via crystallization and supports compatibility with standard coupling protocols.

General Information

CAS No. 1466-83-7
Cat. No. CS-0201820
Purity ≥98%
MDL No. MFCD00190766
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₇NO₃
Molecular Weight 235.28
Synonym(s) None
SMILES CC(C[C@H](NC(C1=CC=CC=C1)=O)C(O)=O)C

Computational Chemistry Data

TPSA 66.4
LogP 1.9157
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Leucine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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N-Benzoyl-L-leucine

CAS No. 1466-83-7

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