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Structure of 615-18-9
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2-Chlorobenzoxazole was used in the synthesis of 2-(2-naphthylamino)benzoxazole via reaction with 2-amino-1-naphthalenesulfonic acid.
2-Chlorobenzoxazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its chlorine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures. The benzoxazole core exhibits excellent bench stability, moderate solubility in common organic solvents, and tolerance to a range of functional groups, making it well-suited for iterative synthesis and late-stage functionalization in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: