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Structure of 1467-86-3
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6-Methylbenzo[b]thiophene-2-carboxylic acid features a fused benzothiophene core with a methyl group at the 6-position and a carboxylic acid function at the 2-position. This electron-deficient heteroaromatic scaffold offers enhanced solubility and stability in synthetic transformations, enabling direct incorporation into pharmaceutical intermediates and functional materials through amide or ester coupling reactions.
6-Methylbenzo[b]thiophene-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its carboxylic acid functionality enables direct derivatization via amide, ester, or acyl chloride formation, while the fused benzo[b]thiophene core provides structural rigidity and favorable electronic properties. The methyl group at the 6-position offers a site for further functionalization or modulation of lipophilicity. The compound exhibits good bench stability and facilitates purification by standard techniques such as recrystallization or column chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: