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Structure of 1735-13-3
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4-Methylbenzo[b]thiophene-2-carboxylic acid integrates a fused thiophene core with a methyl-substituted benzene ring and a carboxylic acid group at the 2-position, delivering enhanced electronic delocalization and solubility. This structure enables direct incorporation into bioactive scaffolds, particularly in kinase inhibitors and fluorescent probes. The compound exhibits robust stability under standard bench conditions and responds predictably to common coupling reactions.
4-Methylbenzo[b]thiophene-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization, while the methyl group enhances metabolic stability. The fused benzo[b]thiophene core provides structural rigidity and favorable π-stacking interactions, making it valuable in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: