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CS-W001157 4
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2-(2H-1,2,3-Triazol-2-yl)ethan-1-ol

  • CAS No. 146984-27-2

  • Cat. No. CS-0095268
  • Purity≥97%
  • MDL No.MFCD03840803

*For research and further manufacturing use only, not for direct human use.

2-(2H-1,2,3-Triazol-2-yl)ethan-1-ol|CS-0095268

Structure of 146984-27-2

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General Information

  • CAS No. 146984-27-2
  • Cat. No. CS-0095268
  • Purity ≥97%
  • MDL No. MFCD03840803
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇N₃O
  • Molecular Weight 113.12
  • Synonym(s) 2H-1,2,3-Triazole-2-ethanol
  • SMILES OCCN1N=CC=N1

Description

This 2-(2H-1,2,3-triazol-2-yl)ethan-1-ol features a reactive triazole moiety paired with a terminal hydroxyl group, enabling efficient conjugation in bioorthogonal labeling. The molecule exhibits excellent solubility in aqueous and polar organic solvents, maintaining stability under standard bench conditions.

Application

2-(2H-1,2,3-Triazol-2-yl)ethan-1-ol serves as a versatile building block in click chemistry and heterocyclic synthesis. Its hydroxyl group enables derivatization and purification via standard chromatographic methods, while the triazolyl moiety offers excellent stability and orthogonal reactivity. Functions effectively in copper-catalyzed azide-alkyne cycloadditions and acts as a key scaffold for bioconjugation and medicinal chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.94
  • LogP   -0.7296
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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