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Structure of 14763-60-1
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4-(Methylsulfonyl)phenol features a phenolic hydroxyl group flanked by a strongly electron-withdrawing methylsulfonyl substituent at the para position. This combination imparts enhanced acidity and stability, enabling direct use in electrophilic substitution reactions and as a building block for functionalized aryl scaffolds in medicinal chemistry and materials science.
4-(Methylsulfonyl)phenol serves as a versatile building block in medicinal chemistry and materials science, enabling the introduction of a polar, electron-withdrawing sulfone group at the para position of an aromatic ring. Its stability under standard reaction conditions facilitates downstream functionalization, including nucleophilic substitution and metal-catalyzed coupling reactions. The compound exhibits excellent solubility in common organic solvents and is readily purified by recrystallization or chromatography, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: