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CS-W001157 4
Total: USD 88.00

2-Amino-4-methylphenol

  • CAS No. 95-84-1

  • Cat. No. CS-W004057
  • Molecule weight123.15
  • Purity≥98%
  • MDL No.MFCD00007699

*For research and further manufacturing use only, not for direct human use.

2-Amino-4-methylphenol|CS-W004057

Structure of 95-84-1

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General Information

  • CAS No. 95-84-1
  • Cat. No. CS-W004057
  • Purity ≥98%
  • MDL No. MFCD00007699
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.15
  • Synonym(s) O-Amino-P-Methylphenol
  • SMILES CC1=CC(N)=C(O)C=C1

Description

2-Amino-4-methylphenol is the major sensitizer in contact allergy to Disperse Yellow 3. It reacts with acetylacetone in absolute ethanol to yield 4-(2-hydroxy-5-methylphenyl)imino-2-pentanone. It was converted to dihydrophenoxazinone by purified human hemoglobin.2-Amino-4-methylphenol was used in the synthesis of novel functionalized spiropyran derivatives of 2H-1,3-benzoxazinone series.

Synthesis

  • Route1
    • null|null
      119-33-5
    • ~99%
    • In-stock
      2-Amino-4-methylphenol|CS-W004057
      95-84-1

    References

    • VICURON PHARMACEUTICALS INC. Patent: US2006/211603 A1, 2006 ; Location in patent: Page/Page column 68 ;
  • Route2

    References

    • Bioorganic and Medicinal Chemistry, , vol. 20, # 5 p. 1679 - 1689
  • Route3
    • tert-Butyl (2-hydroxy-5-methylphenyl)carbamate|CS-0531568
      191112-67-1
    • ~77%
    • In-stock
      2-Amino-4-methylphenol|CS-W004057
      95-84-1

    References

    • Evans, Emily F.; Lewis, Norman J.; Kapfer, Isabelle; Macdonald, Gregor; Taylor, Richard J. K. Synthetic Communications, 1997 , vol. 27, # 11 p. 1819 - 1825

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.28282
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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