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Structure of 1486485-62-4
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3-Methyl-1-(oxan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole is a bench-stable boronate reagent featuring a pyrazole core with orthogonal functional handles. The oxan-2-yl group enhances solubility in polar solvents, while the tetramethyl-substituted dioxaborolane moiety enables efficient coupling under mild conditions. This structure integrates seamlessly into Suzuki-Miyaura cross-coupling workflows, delivering high functional group tolerance and predictable regiochemistry.
3-Methyl-1-(oxan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole core provides structural stability and moderate basicity, while the oxan-2-yl group enhances solubility and modulates reactivity. The pinacol boronate moiety enables robust coupling under mild conditions, with excellent functional group tolerance and bench stability, making it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: