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Structure of 937048-76-5
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tert-Butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate is a bench-stable boronate ester that integrates seamlessly into Suzuki-Miyaura cross-coupling reactions. This molecule features a protected dihydroisoquinoline core flanked by a sterically hindered tetramethylboronate group, enabling selective coupling under mild conditions with high functional group tolerance.
tert-Butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The dihydroisoquinoline core provides a privileged scaffold in medicinal chemistry, while the pinacol boronate group enables efficient, mild coupling with aryl and vinyl halides. Its bench-stable nature, compatibility with diverse functional groups, and straightforward purification make it ideal for iterative synthesis of complex heterocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: