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CS-W001157 4
Total: USD 88.00

2-(2-Chloroethoxy)acetic acid

  • CAS No. 14869-41-1

  • Cat. No. CS-W006556
  • Purity≥95%
  • MDL No.MFCD17014832

*For research and further manufacturing use only, not for direct human use.

2-(2-Chloroethoxy)acetic acid|CS-W006556

Structure of 14869-41-1

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General Information

  • CAS No. 14869-41-1
  • Cat. No. CS-W006556
  • Purity ≥95%
  • MDL No. MFCD17014832
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClO₃
  • Molecular Weight 138.55
  • Synonym(s) 2-CHLOROETHOXY ACETIC ACID
  • SMILES O=C(O)COCCCl

Description

2-(2-Chloroethoxy)acetic acid features a chloroethyl ether linkage that enhances its reactivity in conjugation chemistries. This polar, bench-stable derivative enables efficient coupling to biomolecules under mild conditions, offering improved solubility and handling compared to traditional ester-based linkers.

Application

2-(2-Chloroethoxy)acetic acid serves as a versatile bifunctional building block, enabling efficient conjugation via its carboxylic acid and reactive chloroether moieties. It facilitates nucleophilic substitution reactions for tethering to amines or thiols, and functions as a precursor in the synthesis of bioactive esters and heterocyclic scaffolds. The molecule exhibits good bench stability and compatibility with standard purification techniques, supporting its use in medicinal chemistry and process-scale derivatization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.3264
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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