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Structure of 31181-53-0
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5-Fluoro-2-methylpyridine serves as a critical building block in medicinal chemistry, offering a unique combination of electron-deficient heterocyclic character and steric control. This bench-stable pyridine derivative integrates readily into pharmaceutical scaffolds, where the fluorine and methyl groups enable tailored electronic and metabolic profiles.
5-Fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via palladium-catalyzed cross-coupling. Its electron-withdrawing fluorine and activating methyl group enhance regioselectivity in electrophilic substitution and facilitate C–H activation processes. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it well-suited for constructing bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: