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Structure of 148870-38-6
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(5-Fluoro-2-methoxyphenyl)methanamine features a fluorinated aromatic core with a methoxy group positioned ortho to the amino-methyl side chain, delivering enhanced metabolic stability and favorable lipophilicity. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry projects targeting CNS agents and kinase inhibitors, where its electronic profile supports target engagement. The compound exhibits bench-stable handling characteristics and compatibility with standard coupling protocols.
(5-Fluoro-2-methoxyphenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy and meta-fluoro substituents provide enhanced metabolic stability and modulate electronic properties for target-directed design. The primary amine functionality facilitates straightforward coupling reactions, while the aromatic scaffold exhibits excellent bench stability and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: