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Structure of 1489-97-0
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Ethyl 1,4-dioxaspiro[4.5]decane-8-carboxylate features a rigid spirocyclic architecture that imparts exceptional stereochemical stability. This scaffold integrates a masked aldehyde equivalent with a pendant ester group, enabling selective transformations in complex molecule synthesis. The bicyclic core resists ring-opening under standard conditions, offering reliable access to functionalized intermediates for medicinal chemistry and natural product derivatization.
Ethyl 1,4-dioxaspiro[4.5]decane-8-carboxylate serves as a versatile bicyclic building block for the synthesis of complex heterocyclic scaffolds and bioactive molecules. Its spirocyclic core provides rigidity and defined stereochemistry, while the ester functionality enables straightforward derivatization via hydrolysis, reduction, or coupling reactions. The molecule exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: