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CS-W001157 4
Total: USD 88.00

7-Trifluoromethoxyisatin

  • CAS No. 149125-30-4

  • Cat. No. CS-W006798
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Trifluoromethoxyisatin|CS-W006798

Structure of 149125-30-4

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Description

7-Trifluoromethoxyisatin delivers a potent electron-deficient scaffold for synthetic and medicinal chemistry. The trifluoromethoxy group enhances metabolic stability and lipophilicity, while the isatin core enables direct participation in cyclization, condensation, and transition-metal-catalyzed coupling reactions under standard conditions.

Application

7-Trifluoromethoxyisatin serves as a versatile building block in medicinal chemistry, enabling direct incorporation of electron-withdrawing trifluoromethoxy functionality into heterocyclic scaffolds. Its stability under standard reaction conditions facilitates diverse transformations, including N-alkylation, condensation with amines, and participation in cycloaddition reactions. The compound functions effectively in the synthesis of bioactive molecules, particularly those requiring enhanced metabolic stability and membrane permeability.

General Information

  • CAS No. 149125-30-4
  • Cat. No. CS-W006798
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₄F₃NO₃
  • Molecular Weight 231.13
  • Synonym(s) 7-TRIFLUOROMETHOXY-ISATIN
  • SMILES O=C1NC2=C(C=CC=C2OC(F)(F)F)C1=O

Computational Chemistry Data

  • TPSA   55.4
  • LogP   1.72
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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