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Structure of 149353-84-4
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4-Piperidin-4-ylbenzoic acid hydrochloride features a rigid aromatic core linked to a piperidine moiety, delivering enhanced solubility and metabolic stability. This zwitterionic structure facilitates efficient integration into bioactive scaffolds, particularly in kinase inhibitors and CNS-targeted pharmaceuticals. The hydrochloride salt ensures excellent crystallinity and handling under standard bench conditions.
4-Piperidin-4-ylbenzoic acid hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amide coupling and functional group interconversions. The piperidine moiety provides a basic nitrogen for salt formation and enhanced solubility, while the carboxylic acid facilitates conjugation with peptides, heterocycles, and other pharmacophores. Its bench-stable hydrochloride salt form simplifies handling and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: