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CS-W001157 4
Total: USD 88.00

Potassium trifluoro(3-(trifluoromethyl)benzyl)borate

  • CAS No. 1494466-25-9

  • Cat. No. CS-0362602
  • Purity≥97%
  • MDL No.MFCD18712965
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(3-(trifluoromethyl)benzyl)borate|CS-0362602

Structure of 1494466-25-9

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Description

Potassium trifluoro(3-(trifluoromethyl)benzyl)borate delivers a sterically accessible trifluoromethylbenzyl boronate moiety, enabling direct functionalization in Suzuki-Miyaura coupling reactions under standard conditions. The electron-deficient aryl group enhances reactivity while maintaining bench stability and moisture tolerance, streamlining synthesis of complex fluorinated architectures.

Application

Potassium trifluoro(3-(trifluoromethyl)benzyl)borate serves as a stable, bench-ready boron reagent for palladium-catalyzed cross-coupling reactions. It facilitates efficient C–C bond formation with aryl and vinyl halides, enabling direct introduction of the 3-(trifluoromethyl)benzyl group into complex molecular architectures. The trifluoromethyl substituent enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry lead optimization. Its high functional group tolerance and ease of handling streamline synthetic workflows.

General Information

  • CAS No. 1494466-25-9
  • Cat. No. CS-0362602
  • Purity ≥97%
  • MDL No. MFCD18712965
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BF₆K
  • Molecular Weight 266.03
  • Synonym(s) None
  • SMILES F[B-](F)(CC1=CC=CC(C(F)(F)F)=C1)F.[K+]

Computational Chemistry Data

  • TPSA   0
  • LogP   0.6385
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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