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Structure of 1494466-25-9
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Potassium trifluoro(3-(trifluoromethyl)benzyl)borate delivers a sterically accessible trifluoromethylbenzyl boronate moiety, enabling direct functionalization in Suzuki-Miyaura coupling reactions under standard conditions. The electron-deficient aryl group enhances reactivity while maintaining bench stability and moisture tolerance, streamlining synthesis of complex fluorinated architectures.
Potassium trifluoro(3-(trifluoromethyl)benzyl)borate serves as a stable, bench-ready boron reagent for palladium-catalyzed cross-coupling reactions. It facilitates efficient C–C bond formation with aryl and vinyl halides, enabling direct introduction of the 3-(trifluoromethyl)benzyl group into complex molecular architectures. The trifluoromethyl substituent enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry lead optimization. Its high functional group tolerance and ease of handling streamline synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: