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CS-W001157 4
Total: USD 88.00

Potassium trifluoro[(4-fluorophenyl)methyl]boranuide

  • CAS No. 1494466-28-2

  • Cat. No. CS-0210196
  • Molecule weight216.03
  • Purity≥98%
  • MDL No.MFCD04112715

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro[(4-fluorophenyl)methyl]boranuide|CS-0210196

Structure of 1494466-28-2

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General Information

  • CAS No. 1494466-28-2
  • Cat. No. CS-0210196
  • Purity ≥98%
  • MDL No. MFCD04112715
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BF₄K
  • Molecular Weight 216.03
  • Synonym(s) Potassium trifluoro(4-fluorobenzyl)borate
  • SMILES [F-][B+3]([F-])([F-])[CH2-]C(C=C1)=CC=C1F.[K+]

Description

Potassium trifluoro(4-fluorophenyl)methylboranuide delivers a stable, bench-ready boron source for cross-coupling reactions. The para-fluorophenyl group enhances electron-withdrawing character, enabling efficient palladium-catalyzed transformations. This reagent combines high functional group tolerance with moisture-resistant handling, streamlining synthesis in complex molecular architectures.

Application

Potassium trifluoro[(4-fluorophenyl)methyl]boranuide serves as a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. It exhibits high functional group tolerance and facilitates efficient C–C bond formation with aryl and heteroaryl halides under mild conditions. The fluorinated benzyl moiety enhances solubility and reactivity while maintaining compatibility with common reaction protocols. This reagent enables reliable access to biaryl architectures prevalent in pharmaceutical and agrochemical scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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