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2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline

  • CAS No. 1496-40-8

  • Cat. No. CS-0128719
  • Purity≥95%
  • MDL No.MFCD00042161

*For research and further manufacturing use only, not for direct human use.

2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline|CS-0128719

Structure of 1496-40-8

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General Information

  • CAS No. 1496-40-8
  • Cat. No. CS-0128719
  • Purity ≥95%
  • MDL No. MFCD00042161
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅F₃N₂
  • Molecular Weight 244.26
  • Synonym(s) 2-(1-Piperidinyl)-5-(Trifluoromethyl)Aniline
  • SMILES NC1=CC(C(F)(F)F)=CC=C1N2CCCCC2

Synthesis

  • Route1

    References

    • HAGIWARA, Masatoshi Patent: EP1712242 A1, 2006 ; Location in patent: Page/Page column 18; 30 ;
  • Route2
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      110-89-4
    • ~%
    • 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline|CS-0128719
      1496-40-8

    References

    • Journal of Medicinal Chemistry, , vol. 50, # 4 p. 627 - 640
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 50, # 4 p. 627 - 640

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   3.2779
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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