Lot numbers can be found on the outside label of a product:
tert-Butyl (1-aminopropan-2-yl)carbamate
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CAS No. 149632-73-5
- Cat. No. CS-W005587
- Purity≥95%
- MDL No.MFCD16660178
*For research and further manufacturing use only, not for direct human use.
Structure of 149632-73-5
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General Information
- CAS No. 149632-73-5
- Cat. No. CS-W005587
- Purity ≥95%
- MDL No. MFCD16660178
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₈N₂O₂
- Molecular Weight None
- Synonym(s) tert-butyl N-(1-aminopropan-2-yl)carbamate
- SMILES CC(NC(OC(C)(C)C)=O)CN
Description
tert-Butyl (1-aminopropan-2-yl)carbamate delivers a protected serine surrogate with enhanced stability and solubility in organic media. This bench-stable carbamate incorporates a chiral β-amino alcohol scaffold, enabling direct incorporation into peptide sequences or as a building block for bioactive small molecules. The tert-butyl group facilitates convenient deprotection under mild acidic conditions, streamlining synthetic workflows.
Application
tert-Butyl (1-aminopropan-2-yl)carbamate serves as a stable, bench-friendly amino protecting group derivative, enabling selective N-alkylation and amide bond formation under standard conditions. Its tert-butyl carbamate moiety offers orthogonal deprotection compatibility with acid-labile functionalities, facilitating efficient synthesis of complex intermediates in peptide and medicinal chemistry workflows.
Synthesis
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Route1
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149602-64-2 - ~85%
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In-stock
149632-73-5
References
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Gardiner, John M.; Loyns, Colin R. Tetrahedron, 1995 , vol. 51, # 42 p. 11515 - 11530
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References
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GLAXOSMITHKLINE LLC; BANKA, Anna; CATALANO, John, G.; CHONG, Pek, Yoke; FANG, Jing; GARRIDO, Dulce, Maria; PEAT, Andrew, James; PRICE, Daniel, J.; SHOTWELL, John, Brad; TAI, Vincent; ZHANG, Huichang Patent: WO2011/41713 A2, 2011 ; Location in patent: Page/Page column 229 ;
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Route3
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In-stock
24424-99-5 - ~%
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In-stock
149632-73-5
References
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Gardiner, John M.; Loyns, Colin R. Tetrahedron, 1995 , vol. 51, # 42 p. 11515 - 11530
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 64.35
- LogP 0.8583
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 2
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Key Words
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