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Structure of 149649-58-1
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2-Boc-aminomethyl-pyrrolidine features a pyrrolidine core functionalized with a Boc-protected aminomethyl group, enabling direct incorporation into peptide and small-molecule scaffolds. The protected amine facilitates orthogonal handling in multistep syntheses, while the cyclic structure imparts conformational rigidity beneficial for bioactive compound design. This derivative combines synthetic versatility with stability under standard bench conditions.
2-Boc-aminomethyl-pyrrolidine serves as a versatile building block for the synthesis of bioactive nitrogen-containing scaffolds. The Boc group provides excellent stability and ease of removal under mild acidic conditions, enabling straightforward access to the free amine. It functions effectively in amide coupling, reductive amination, and nucleophilic substitution reactions, offering high functional group tolerance and compatibility with standard synthetic workflows. Its rigid pyrrolidine core enhances conformational control in target molecules, making it valuable in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: