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(4-(Pyridin-2-yl)phenyl)methanamine hydrochloride

  • CAS No. 1498333-87-1

  • Cat. No. CS-0141579
  • Molecule weight220.70
  • Purity≥95%
  • MDL No.MFCD27923416

*For research and further manufacturing use only, not for direct human use.

(4-(Pyridin-2-yl)phenyl)methanamine hydrochloride|CS-0141579

Structure of 1498333-87-1

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General Information

  • CAS No. 1498333-87-1
  • Cat. No. CS-0141579
  • Purity ≥95%
  • MDL No. MFCD27923416
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃ClN₂
  • Molecular Weight 220.70
  • Synonym(s) (4-(PYRIDIN-2-YL)PHENYL)METHANAMINE HCL
  • SMILES NCC1=CC=C(C2=NC=CC=C2)C=C1.[H]Cl

Description

This bench-stable amine features a pyridyl-phenyl scaffold enabling strong coordination in catalytic systems. The hydrochloride salt enhances solubility in polar media while maintaining structural integrity under standard handling conditions.

Application

(4-(Pyridin-2-yl)phenyl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry and materials science, enabling efficient construction of biaryl scaffolds via standard coupling reactions. The amine functionality offers high reactivity in amidations, alkylations, and electrophilic substitutions, while the pyridine and phenyl moieties provide enhanced solubility and π-stacking potential. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses requiring robust nitrogen-containing aryl intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.6291
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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