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Structure of 150322-73-9
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1-Cyclopropyl-2-(2-fluorophenyl)ethanone features a fluorinated aromatic ring paired with a cyclopropyl ketone moiety, enabling enhanced metabolic stability and favorable lipophilic character. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS disorders and kinase inhibition, where its steric profile and electronic modulation support improved target engagement.
1-Cyclopropyl-2-(2-fluorophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its aryl ketone functionality supports standard transformations including nucleophilic additions, reductions, and coupling reactions. The cyclopropyl group enhances metabolic stability and modulates lipophilicity, while the ortho-fluorophenyl moiety provides favorable electronic and steric properties for target engagement. This compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: