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CS-W001157 4
Total: USD 88.00

3-Hydroxy-2-pyrrolidinone

  • CAS No. 15166-68-4

  • Cat. No. CS-W005201
  • Purity≥98%
  • MDL No.MFCD09751256
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-2-pyrrolidinone|CS-W005201

Structure of 15166-68-4

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Description

3-Hydroxy-2-pyrrolidinone is a polar, bench-stable heterocyclic compound featuring a hydroxyl group at the 3-position and a lactam carbonyl at the 2-position. This structural motif enables efficient integration into peptide mimetics and bioactive molecule scaffolds, offering enhanced solubility and metabolic stability in synthetic workflows.

Application

3-Hydroxy-2-pyrrolidinone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its amide functionality and hydroxyl group offer orthogonal reactivity for selective derivatization, while its inherent stability facilitates handling and purification. This scaffold functions effectively in coupling reactions and cyclization processes, supporting scalable synthesis of complex molecular architectures.

General Information

  • CAS No. 15166-68-4
  • Cat. No. CS-W005201
  • Purity ≥98%
  • MDL No. MFCD09751256
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.10
  • Synonym(s) 3-Hydroxy-2-oxo-pyrrolidin
  • SMILES O=C1NCCC1O

Computational Chemistry Data

  • TPSA   49.33
  • LogP   -1.1328
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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