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CS-W001157 4
Total: USD 88.00

5-Chloro-1-methyl-1H-pyrazolo[3,4-c]pyridine

  • CAS No. 1521237-92-2

  • Cat. No. CS-0045107
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1-methyl-1H-pyrazolo[3,4-c]pyridine|CS-0045107

Structure of 1521237-92-2

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General Information

  • CAS No. 1521237-92-2
  • Cat. No. CS-0045107
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆ClN₃
  • Molecular Weight 167.60
  • Synonym(s) None
  • SMILES CN1N=CC2=C1C=NC(Cl)=C2

Description

5-Chloro-1-methyl-1H-pyrazolo[3,4-c]pyridine is a heterocyclic scaffold featuring a chlorine substituent at the 5-position and a methyl group at the 1-position, enhancing electron deficiency and metabolic stability. This framework integrates readily into medicinal chemistry libraries, serving as a core building block for kinase inhibitors and CNS-targeted therapeutics.

Application

5-Chloro-1-methyl-1H-pyrazolo[3,4-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its chloro group enables palladium-catalyzed cross-coupling reactions, while the methyl-substituted pyrazolopyridine core offers enhanced metabolic stability and favorable pharmacokinetic properties. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard coupling protocols, making it a practical choice for scaffold diversification in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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Computational Chemistry Data

  • TPSA   30.71
  • LogP   1.6217
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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